Integrin is the molecule that connects the outside of the cells to the extracellular matrix. |
Expression of the membrane protein that binds laminin, integrin, also becomes irregular at the beginning of ingression. |
Understanding the nature of the interaction between the integrin and cell adhesion molecules can aid in the design of potent therapeutics. |
Several cytosolic proteins compete for integrin binding to regulate activation, endocytosis and recycling. |