Mercuriation of nucleic acids is performed after ISH is completed using haptens with SH groups that bing the mercury. |
Toxic metabolites form haptens with tissue proteins and produce neoantigens, such as the formation of reactive hydroxylamines from sulfonamides. |
Supporting this is the discovery by Vojdani et al., who reported that some individuals develop allergic antibodies to haptens formed in response to MTBE binding to albumin. |
The bound microparticle complexes are then incubated with antidetection hapten alkaline phosphatase conjugate, which binds to the detection haptens. |
Filaggrin deficiency confers a paracellular barrier abnormality that reduces nflammatory thresholds to irritants and haptens. |
This phenomenon is clinically well known as anergy to tuberculin or other immunogenic haptens after subcutaneous injections. |