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What does derangement mean?

Looking for the meaning or definition of the word derangement? Here's what it means.

Noun
  1. The property of being deranged.
  2. An act or instance of deranging.
  3. (mathematics) A permutation of a set such that no element is in its previous position.
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Examples
The influence of this as an etiological factor in derangement of digestion can scarcely be exaggerated.
The majority of cases of acute internal derangement will be obvious within a few days.
Thus, the combination of obesity with a genetically-based insulin derangement, may reveal latent diabetes.
Enrique's face is twisted into a rictus grin, and he lets out the unmistakable chortle of sheer psychotic derangement.
And viciousness or crime are the result of a derangement in the primary system.
She points out that only a proportion of its patients have been ordered there by a court after committing an offence through mental derangement.

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