| Through inhibition of the cyclooxygenase pathway of arachidonate metabolism, NSAIDs prevent the production of the proinflammatory prostaglandins. |
| Apocynin prevents cyclooxygenase 2 expression in human monocytes through NADPH oxidase and glutathione redox-dependent mechanisms. |
| Aspirin inhibits platelet aggregation by blocking cyclooxygenase in the archidonic acid pathway, which inhibits the formation of thromboxane A2 in platelets. |
| In vitro inhibition of cyclooxygenase and 5-lipoxygenase by alkamides from Echinacea and Achillea species. |
| Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. |
| Compound 4 showed better or comparable cyclooxygenase enzyme inhibition than positive controls. |
